CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Genetic Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) in Orthotopic Liver Transplant Recipients are Determinants for Elevated Serum Homocysteine and Vascular Complications
DOI 10.1055/s-2004-831808
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Autor:innenB Akoglu, P Kindl, K Wondra, N Weber, J Trojan, WF Caspary, D Faust
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Hyperhomocysteinemia is a known risk factor of cardiovascular diseases and is frequently associated with impaired folate metabolism. C677T polymorphism in the methyltetrahydrofolate reductase (MTHFR) gene, which is a key enzyme in folate metabolism, results in thermolability, decreased enzyme activity and hyperhomocysteinemia. MTHFR distribution in the general population is 45% for the wild type (CC), 45% for the he…
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Zitierempfehlung
B Akoglu, P Kindl, K Wondra, N Weber, J Trojan, WF Caspary, D Faust (2004) Genetic Polymorphisms in the Methylenetetrahydrofolate Reductase Gene (MTHFR) in Orthotopic Liver Transplant Recipients are Determinants for Elevated Serum Homocysteine and Vascular Complications. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-2004-831808
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