CareLit · DOI-Nachweis · Klinische Neurophysiologie
Telomere Lagging Strand Synthesis Dysfunction in Cells Lacking WRN Helicase Activity
DOI 10.1055/s-2004-832038
Bibliografische Angaben
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Autor:innenJ Karlseder, L Crabbe, R Verdun, C Haggblom
ZeitschriftKlinische Neurophysiologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Werner syndrome is an autosomal recessive disease, and individuals suffering from the syndrome show all signs of premature ageing. Cells from Werner Syndrome patients are characterized by slow growth rates, premature senescence, accelerated telomere shortening rates and genome instability. The syndrome is caused by the loss of the RecQ helicase WRN, but the underlying molecular mechanism is unclear. Here, we report…
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Zitierempfehlung
J Karlseder, L Crabbe, R Verdun, C Haggblom (2004) Telomere Lagging Strand Synthesis Dysfunction in Cells Lacking WRN Helicase Activity. Klinische Neurophysiologie (08). https://doi.org/10.1055/s-2004-832038
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