CareLit · DOI-Nachweis · Klinische Neurophysiologie
Targeting Prion Protein and Alzheimer's disease Amyloid Peptide by Peptide Ligands
DOI 10.1055/s-2004-832232
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Willbold, K Wiesehan, K Haenel, S Patt, RP Linke
ZeitschriftKlinische Neurophysiologie
Ausgabe08/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The presently established models of prion propagation are based on the essential role of the host-encoded prion protein (PrP). Development and progression of the disease implies ongoing conversion of its non-pathological isoform PrPC into its pathological isoform PrPSc. Thus, any stabilization of the PrPC conformation should slow down or inhibit conversion of PrPC into PrPSc. We screened a phage displayed peptide li…
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Zitierempfehlung
D Willbold, K Wiesehan, K Haenel, S Patt, RP Linke (2004) Targeting Prion Protein and Alzheimer's disease Amyloid Peptide by Peptide Ligands. Klinische Neurophysiologie (08). https://doi.org/10.1055/s-2004-832232
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