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Compounds that inhibit amyloid formation of Huntington's and Alzheimer's disease proteins imply a common aggregation pathway

M Herbst, S Engemann, J Walther, R Lurz, V Heiser, EE Wanker · Aktuelle Neurologie · Ausgabe 09/2004

DOI 10.1055/s-2004-832977

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Autor:innenM Herbst, S Engemann, J Walther, R Lurz, V Heiser, EE Wanker
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Amyloid formation is widely accepted to play a crucial role in the pathogenesis of many neurodegenerative disorders including Alzheimer's disease (AD) and polyglutamine disorders such as Huntington's disease. The disease-specific amyloid-forming proteins share no sequence homologies and have different functions. However, recent studies demonstrated strong similarities in the process of protein aggregation despite th…

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M Herbst, S Engemann, J Walther, R Lurz, V Heiser, EE Wanker (2004) Compounds that inhibit amyloid formation of Huntington's and Alzheimer's disease proteins imply a common aggregation pathway. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-832977

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