CareLit · DOI-Nachweis · Aktuelle Neurologie
Brain-selective VEGF overexpression induces post-ischemic neuroprotection, but also facilitates hemodynamic steal phenomena
DOI 10.1055/s-2004-832992
Bibliografische Angaben
Nachweis in CareLit
Autor:innenY Wang, E Kilic, Ü Kilic, C Bassetti, H Marti, D Hermann
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Therapeutic angiogenesis with vascular endothelial growth factor (VEGF) is a clinically promising strategy in ischemic disease. The pathophysiological consequences of enhanced vessel formation, however, are poorly understood. Methods: We here established mice overexpressing human VEGF165 under a neuron-specific NSE promoter, which exhibited an increased density of brain vessels under physiological condit…
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Zitierempfehlung
Y Wang, E Kilic, Ü Kilic, C Bassetti, H Marti, D Hermann (2004) Brain-selective VEGF overexpression induces post-ischemic neuroprotection, but also facilitates hemodynamic steal phenomena. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-832992
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