CareLit · DOI-Nachweis · Aktuelle Neurologie
Reversal of L-DOPA-induced dyskinesia by recombinant AAV-mediated gene transfer
DOI 10.1055/s-2004-833029
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Autor:innenC Winkler, T Carlsson, C Burger, N Muzyczka, R Mandel, A Cenci, R Dengler, A Björklund, D Kirik
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objective: To reduce L-DOPA-induced dyskinesia by viral vector gene transfer. Background: Long-term L-DOPA treatment in Parkinson's disease can induce severe dyskinesia in Parkinsonian patients. The appearance of dyskinesia is at least in part due to the intermittent pulsatile administration of L-DOPA, since continuous infusion of L-DOPA in patients can reduce L-DOPA-induced dyskinesia. Methods: In this study we use…
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Zitierempfehlung
C Winkler, T Carlsson, C Burger, N Muzyczka, R Mandel, A Cenci, R Dengler, A Björklund, D Kirik (2004) Reversal of L-DOPA-induced dyskinesia by recombinant AAV-mediated gene transfer. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-833029
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