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A two-year clinical follow-up study in 80 CADASIL subjects: progression patterns and implications for clinical trials

J Herzog, N Peters, C Opherk, M Dichgans · Aktuelle Neurologie · Ausgabe 09/2004

DOI 10.1055/s-2004-833048

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Autor:innenJ Herzog, N Peters, C Opherk, M Dichgans
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background and Purpose: CADASIL is a monogenic form of small vessel disease leading to stroke and dementia. The goal of this study was to explore the natural course of the disease, to check for prognostic variables, and to provide sample size estimates for future therapeutic trials. Methods: Eighty CADASIL subjects were followed prospectively over a mean period of 26.3+1.1 months. Standardized scales on disability (…

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J Herzog, N Peters, C Opherk, M Dichgans (2004) A two-year clinical follow-up study in 80 CADASIL subjects: progression patterns and implications for clinical trials. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-833048

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