CareLit · DOI-Nachweis · Aktuelle Neurologie
Conditional control of human wild-type and Parkinson's disease-associated mutant alpha-synuclein in transgenic mouse brain
DOI 10.1055/s-2004-833272
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Autor:innenS Nuber, T Schmidt, D Berg, M Neumann, C Holzmann, M Fendt, U Grasshoff, I Schmitt, A Bornemann, F Zimmermann, W Kuhn, SB Prusiner, M Bonin, A Servadio, O Riess
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The presynaptic protein alpha-synuclein has been implicated in the pathophysiology of many neurodegenerative disorders, including Parkinson's Disease and dementia with Lewy bodies, collectively referred to as synucleinopathies. To advance the study of the function of alpha-synuclein in these diseases, we have used the tTA-system to generate transgenic mice, which express human wildtype or mutated [A30P] alpha-synucl…
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Zitierempfehlung
S Nuber, T Schmidt, D Berg, M Neumann, C Holzmann, M Fendt, U Grasshoff, I Schmitt, A Bornemann, F Zimmermann, W Kuhn, SB Prusiner, M Bonin, A Servadio, O Riess (2004) Conditional control of human wild-type and Parkinson's disease-associated mutant alpha-synuclein in transgenic mouse brain. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-833272
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