CareLit · DOI-Nachweis · Aktuelle Neurologie
Menadione inhibits attenuation of the paracellular permeability of a brain endothelioma cell monolayer by interferon-beta in vitro
DOI 10.1055/s-2004-833326
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Voigt, J Kraus, P Oschmann, B Engelhardt, M Clauss
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Breakdown of the blood-brain barrier (BBB) is an essential part of the pathogenesis of multiple sclerosis (MS). BBB function can be impaired by free radicals in vitro, and free radicals are highly elevated in patients with acute exacerbations of MS. Menadione can cross the lipid bilayer and is therefore considered as an intracellular oxyradical producing agent. We have shown previously that low-dose inte…
Zitieren
Zitierempfehlung
K Voigt, J Kraus, P Oschmann, B Engelhardt, M Clauss (2004) Menadione inhibits attenuation of the paracellular permeability of a brain endothelioma cell monolayer by interferon-beta in vitro. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-833326
Mit CareLit weiterarbeiten