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Assessment of potential cardiotoxic side effects of mitoxantrone in patients with multiple sclerosis – an interim analysis after five years

A Gross, M Strupp, VC Zingler, M Näbauer, K Jahn, R Hohlfeld, T Brandt · Aktuelle Neurologie · Ausgabe 09/2004

DOI 10.1055/s-2004-833328

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Autor:innenA Gross, M Strupp, VC Zingler, M Näbauer, K Jahn, R Hohlfeld, T Brandt
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben

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Introduction: Several studies have shown that mitoxantrone (mitox) may have beneficial effect on the course of disease in patients with multiple sclerosis (MS). There is, however, concern that its potentially cumulative cardiotoxic side effects may cause cardiomyopathy, reduced left ventricular (LV) ejection fraction (EF), and irreversible congestive heart failure (CHF). Therefore the aim of this study was to invest…

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A Gross, M Strupp, VC Zingler, M Näbauer, K Jahn, R Hohlfeld, T Brandt (2004) Assessment of potential cardiotoxic side effects of mitoxantrone in patients with multiple sclerosis – an interim analysis after five years. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-833328

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