CareLit · DOI-Nachweis · Aktuelle Neurologie
Mechanisms of homocysteine (neuro)toxicity: a novel point of view
DOI 10.1055/s-2004-833381
Bibliografische Angaben
Nachweis in CareLit
Autor:innenU Wüllner, H Lutz, E Jarre, S Vielhaber, T Klockgether, W Kunz, M Linnebank
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hyperhomocysteinemia has been associated with vascular disease and neurodegeneration. We investigated the effects of homocysteine (Hcy) on mitochrondrial electron transport chain activity in dopaminergic rat pheochromocytoma (PC12) cells. Hcy dose-dependently induced apoptotic cell death. However, with LD50 dosage, no significant induction of reactive oxygen species occurred and Complex I activity was only marginall…
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Zitierempfehlung
U Wüllner, H Lutz, E Jarre, S Vielhaber, T Klockgether, W Kunz, M Linnebank (2004) Mechanisms of homocysteine (neuro)toxicity: a novel point of view. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-833381
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