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Failure to enhance thrombolytic therapy by neuroprotection with memantine in a model of embolic stroke

T Back, D Otto, D Kittner, T Hemmen, WH Oertel · Aktuelle Neurologie · Ausgabe 09/2004

DOI 10.1055/s-2004-833441

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Autor:innenT Back, D Otto, D Kittner, T Hemmen, WH Oertel
ZeitschriftAktuelle Neurologie
Ausgabe09/2004
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: To combine neuroprotective drugs with recanalizing therapy seems to be an excellent rationale to improve stroke therapy and outcome. However, experimental data employing an embolic stroke model with suboptimal reperfusion rates – as present after thrombolysis in human stroke patients – are not available. We hypothetized that the combined use of tissue plasminogen activator (t-PA) and memantine (NMDA rece…

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Zitierempfehlung

T Back, D Otto, D Kittner, T Hemmen, WH Oertel (2004) Failure to enhance thrombolytic therapy by neuroprotection with memantine in a model of embolic stroke. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2004-833441

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