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Regulation of Rat Heme Oxygenase–1 Gene Expression by Interleukin–6 via Jak/STAT Pathway

K Tron, A Samoylenko, G Musikowski, F Kobe, S Immenschuh, F Schaper, G Ramadori, T Kietzmann · Zeitschrift für Gastroenterologie · Ausgabe 01/2005

DOI 10.1055/s-2005-861609

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Autor:innenK Tron, A Samoylenko, G Musikowski, F Kobe, S Immenschuh, F Schaper, G Ramadori, T Kietzmann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background and Aims: Heme oxygenase–1 (HO–1) is the inducible enzyme that catalyzes oxidative degradation of heme. It has been recently shown that HO–1 expression is up-regulated in the liver by proinflammatory cytokines. However, the signal transduction pathways of the cytokine-dependent HO–1 regulation are not known in detail. Therefore, the aim of the present study was to investigate the mechanisms of the IL–6-me…

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K Tron, A Samoylenko, G Musikowski, F Kobe, S Immenschuh, F Schaper, G Ramadori, T Kietzmann (2005) Regulation of Rat Heme Oxygenase–1 Gene Expression by Interleukin–6 via Jak/STAT Pathway. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2005-861609

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