CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
NTCP Down-Regulation During Obstructive Cholestasis Occurs Cytokine-Independently in Rats and Mice
DOI 10.1055/s-2005-861614
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Geier, G Zollner, CG Dietrich, M Wagner, P Fickert, N van Rooijen, H Denk, S Matern, C Gartung, M Trauner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cholestatic liver injury is a complex pathophysiologic situation not only associated with accumulation of bile acids but also with activation of proinflammatory cytokines. Common bile duct ligation (CBDL) induces sustained downregulation of the Na+/taurocholate cotransporter (Ntcp) in rat and mouse liver. While repression of Ntcp during endotoxemia is cytokine-mediated (Geier et al. Hepatology 2003), it is unclear w…
Zitieren
Zitierempfehlung
A Geier, G Zollner, CG Dietrich, M Wagner, P Fickert, N van Rooijen, H Denk, S Matern, C Gartung, M Trauner (2005) NTCP Down-Regulation During Obstructive Cholestasis Occurs Cytokine-Independently in Rats and Mice. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2005-861614
Mit CareLit weiterarbeiten