CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
All-trans-Retinoic Acid for Treatment of Patients with Chronic Hepatitis C and Non-Response to Interferon-alfa/Ribavirin
DOI 10.1055/s-2005-862286
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Nachweis in CareLit
Autor:innenWO Böcher, C Wallasch, T Herget, B Klebel, P Galle
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In vitro studies, submitted in parallel by Herget et al, have shown that all-trans retinoic acid (ATRA) induces upregulation of selenium dependent gastrointestinal-glutathione peroxidase in HCV-subgenomic RNA replicon cells leading to drastic downregulation of the replicon, that was further enhanced by interferon alfa. Based on these findings, a clinical pilot trial was performed in HCV non-responder p…
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Zitierempfehlung
WO Böcher, C Wallasch, T Herget, B Klebel, P Galle (2005) All-trans-Retinoic Acid for Treatment of Patients with Chronic Hepatitis C and Non-Response to Interferon-alfa/Ribavirin. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-2005-862286
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