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Monocyte chemoattractant protein MCP-1 gene polymorphism in Sarcoidosis

KI Gaede, DV Pechkovsky, G Zissel, J Müller-Quernheim · Pneumologie · Ausgabe 01/2005

DOI 10.1055/s-2005-862735

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Autor:innenKI Gaede, DV Pechkovsky, G Zissel, J Müller-Quernheim
ZeitschriftPneumologie
Ausgabe01/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Monocyte chemoattractant protein (MCP)-1 is expressed by monocytes and human pulmonary type-2 epithelial cells and many others. This CC chemokine exhibits chemotactic activity towards macrophages/ monocytes and induces the production of inflammatory cytokines affecting granuloma formation, which is of interest in sarcoidosis. Recently, a biallelic A/ G polymorphism has been found in the distal regulatory…

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KI Gaede, DV Pechkovsky, G Zissel, J Müller-Quernheim (2005) Monocyte chemoattractant protein MCP-1 gene polymorphism in Sarcoidosis. Pneumologie (01). https://doi.org/10.1055/s-2005-862735

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