CareLit · DOI-Nachweis · Pneumologie
Reversal of pulmonary vascular remodeling induced by hypoxia in mice by the soluble guanylate cyclase activator Bay 58–2667
DOI 10.1055/s-2005-864285
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Schermuly, R Dumitrascu, JP Stasch, A Ghofrani, F Grimminger, W Seeger, N Weissmann
ZeitschriftPneumologie
Ausgabe03/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Severe pulmonary hypertension is a disabling disease with high mortality. We investigated the effects of the soluble guanylate cyclase activator Bay 58–2667 on hemodynamics and vascular remodeling in hypoxia-induced pulmonary hypertension in mice. Twenty-one and 35 days after chronic hypoxia (10 % O2), right ventricular systolic pressure (RVSP) increased from 22,4±2,0 to 38,9±3,8 and 44,3±5,2mm Hg, respectively. Mar…
Zitieren
Zitierempfehlung
R Schermuly, R Dumitrascu, JP Stasch, A Ghofrani, F Grimminger, W Seeger, N Weissmann (2005) Reversal of pulmonary vascular remodeling induced by hypoxia in mice by the soluble guanylate cyclase activator Bay 58–2667. Pneumologie (03). https://doi.org/10.1055/s-2005-864285
Mit CareLit weiterarbeiten