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Association of interleukin 8 receptor alpha polymorphisms with chronic obstructive pulmonary disease and asthma

S Stemmler, U Arinir, W Klein, G Rohde, N Wirkus, G Schultze-Werninghaus, JT Epplen · Pneumologie · Ausgabe 03/2005

DOI 10.1055/s-2005-864322

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Autor:innenS Stemmler, U Arinir, W Klein, G Rohde, N Wirkus, G Schultze-Werninghaus, JT Epplen
ZeitschriftPneumologie
Ausgabe03/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Chronic obstructive pulmonary disease (COPD) and asthma are common complex diseases characterized by airflow obstruction and inflammatory processes in the small airways. Interleukin 8 (IL-8) is a potent pro-inflammatory cytokine which interacts with the receptors interleukin 8 receptor α (IL8RA, CXCR1) and interleukin 8 receptor β (IL8RB, CXCR2), leading to activation and migration of leukocytes. In order to evaluat…

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Zitierempfehlung

S Stemmler, U Arinir, W Klein, G Rohde, N Wirkus, G Schultze-Werninghaus, JT Epplen (2005) Association of interleukin 8 receptor alpha polymorphisms with chronic obstructive pulmonary disease and asthma. Pneumologie (03). https://doi.org/10.1055/s-2005-864322

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