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Unaltered cell cycle regulation after infection with high-capacity but not first-generation adenoviral vectors

U Liebers, G Wolff, H Lehmkuhl, A Schumacher, C Witt · Pneumologie · Ausgabe 03/2005

DOI 10.1055/s-2005-864615

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Autor:innenU Liebers, G Wolff, H Lehmkuhl, A Schumacher, C Witt
ZeitschriftPneumologie
Ausgabe03/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Rationale: Adenovirus vectors are widely used in experimental and clinical gene transfer studies to the lung. First-generation (E1/E3 deleted) vectors are well documented to induce severe cell cycle dysregulation in target cells. For high-capacity vectors (all viral genes deleted) information about their influence on cell cycle regulation in the target cell are still missing. Methods: We investigated the influence o…

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Zitierempfehlung

U Liebers, G Wolff, H Lehmkuhl, A Schumacher, C Witt (2005) Unaltered cell cycle regulation after infection with high-capacity but not first-generation adenoviral vectors. Pneumologie (03). https://doi.org/10.1055/s-2005-864615

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