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Elevated epithelial insulin-like growth factor receptor I (IGFR-I) and C-MET (hepatocyte growth factor receptor) expression in mild and moderate ulcerative colitis can enhance the survival of genetically defected epithelial cells

F Sipos, E Tihanyi, B Molnár, Z Tulassay · Zeitschrift für Gastroenterologie · Ausgabe 05/2005

DOI 10.1055/s-2005-869765

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Autor:innenF Sipos, E Tihanyi, B Molnár, Z Tulassay
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: IGFR-I and c-met are known to be involved in regenerative/age-related changes in several human tissues, but their correlation to the epithelial layer is not clear. Aims: to examine the role of these proteins in ulcerative colitis (UC) considering of the elevated risk of malignant transformation. Materials and methods: 5µm thick sections of paraffin embedded formalin fixed colonic biopsies from mildly, mo…

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Zitierempfehlung

F Sipos, E Tihanyi, B Molnár, Z Tulassay (2005) Elevated epithelial insulin-like growth factor receptor I (IGFR-I) and C-MET (hepatocyte growth factor receptor) expression in mild and moderate ulcerative colitis can enhance the survival of genetically defected epithelial cells. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-2005-869765

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