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Analysis of alpha-synuclein aggregation and associated pathologies in a cellular model of multiple system atrophy

G Fillon, M Neumann, R Zufferey, P Aebischer, HA Kretzschmar, C Lubetzki, B Zalc, C Haass, PJ Kahle · Aktuelle Neurologie · Ausgabe 09/2005

DOI 10.1055/s-2005-916295

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Autor:innenG Fillon, M Neumann, R Zufferey, P Aebischer, HA Kretzschmar, C Lubetzki, B Zalc, C Haass, PJ Kahle
ZeitschriftAktuelle Neurologie
Ausgabe09/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Intracellular aggregation of alpha-synuclein is a neuropathological hallmark of a variety of neurodegenerative diseases, including Parkinson's disease and multiple system atrophy (MSA). The deposition of the normally neuronal alpha-synuclein protein within (oligodendro)glial cytoplasmic inclusions (GCIs) and its relationship with oligodendrocyte death in MSA have not been elucidated. We developed a cellular model th…

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Zitierempfehlung

G Fillon, M Neumann, R Zufferey, P Aebischer, HA Kretzschmar, C Lubetzki, B Zalc, C Haass, PJ Kahle (2005) Analysis of alpha-synuclein aggregation and associated pathologies in a cellular model of multiple system atrophy. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2005-916295

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