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Experimental studies and theoretical aspects on A2A/D2 receptor interactions in a model of Parkinson's disease. Relevance for l-dopa induced dyskinesias

T Antonelli, K Fuxe, L Agnati, S Tanganelli, MC Tomasini, L Ferraro · Aktuelle Neurologie · Ausgabe 09/2005

DOI 10.1055/s-2005-916296

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Autor:innenT Antonelli, K Fuxe, L Agnati, S Tanganelli, MC Tomasini, L Ferraro
ZeitschriftAktuelle Neurologie
Ausgabe09/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Dual probe microdialysis in the awake rat has been used to study the role of A2A/D2 receptor interactions in the striato-pallidal GABA pathway in a model of Parkinson Disease (PD).The A2A agonist CGS 21680 and/or the D2 like agonist quinpirole were perfused via reverse microdialysis into the DA denervated striatum and the effects on globus pallidus extracellular GABA levels were evaluated. Evidence was obtained that…

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T Antonelli, K Fuxe, L Agnati, S Tanganelli, MC Tomasini, L Ferraro (2005) Experimental studies and theoretical aspects on A2A/D2 receptor interactions in a model of Parkinson's disease. Relevance for l-dopa induced dyskinesias. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2005-916296

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