CareLit · DOI-Nachweis · Aktuelle Neurologie
KATP channels control the differential vulnerability of dopaminergic midbrain neurons in a chronic MPTP-model of Parkinson's disease
DOI 10.1055/s-2005-916300
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Autor:innenB Liss, O Haeckel, J Wildmann, T Miki, S Seino, J Roeper
ZeitschriftAktuelle Neurologie
Ausgabe09/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The selective and progressive degeneration of dopaminergic (DA) midbrain neurons, in particular within the substantia nigra (SN), is a hallmark of Parkinson's disease (PD) and its animal models. DA neurons in the neighbouring ventral tegmental area (VTA) are significantly less affected. The molecular mechanisms for this differential vulnerability of DA subpopulations are unknown. We have previously shown that acute…
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Zitierempfehlung
B Liss, O Haeckel, J Wildmann, T Miki, S Seino, J Roeper (2005) KATP channels control the differential vulnerability of dopaminergic midbrain neurons in a chronic MPTP-model of Parkinson's disease. Aktuelle Neurologie (09). https://doi.org/10.1055/s-2005-916300
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