CareLit · DOI-Nachweis · Aktuelle Neurologie
Kinetics of vascular normalisation by VEGFR2 blockade governs brain tumour response to radiation: role of angiopoietin-1 and matrix metalloproteinases
DOI 10.1055/s-2005-919261
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Winkler, S Kozin, R Tong, D Hicklin, L Munn, R Jain
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: A recent successful Phase III clinical trial using a VEGF-specific antibody suggests that antiangiogenic therapy must be combined with cytotoxic therapy for the treatment of solid tumors. However, there are no guidelines for optimal scheduling of these therapies. Specifically, Glioblastoma Multiforme is characterized by a dilated, tortuous, disorganized, and leaky vasculature and by high levels of VEGF.…
Zitieren
Zitierempfehlung
F Winkler, S Kozin, R Tong, D Hicklin, L Munn, R Jain (2005) Kinetics of vascular normalisation by VEGFR2 blockade governs brain tumour response to radiation: role of angiopoietin-1 and matrix metalloproteinases. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919261
Mit CareLit weiterarbeiten