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Conditional control of human wildtype and mutated [A30P] alpha-synuclein in a mouse model of Parkinson's disease

S Nuber, T Schmidt, H.W Habbes, M Löbbecke-Schumacher, P Teismann, J.B Schulz, B.J Pichler, M Neumann, M Fendt, D Berg, C Holzmann, U Grasshoff, J Boy, I Schmitt, A Bornemann, F Zimmermann, W Kuhn, S Prusiner, E Petrasch-Parwez, O Riess · Aktuelle Neurologie · Ausgabe 10/2005

DOI 10.1055/s-2005-919318

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Autor:innenS Nuber, T Schmidt, H.W Habbes, M Löbbecke-Schumacher, P Teismann, J.B Schulz, B.J Pichler, M Neumann, M Fendt, D Berg, C Holzmann, U Grasshoff, J Boy, I Schmitt, A Bornemann, F Zimmermann, W Kuhn, S Prusiner, E Petrasch-Parwez, O Riess
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Alpha-synuclein, a small soluble protein is expressed primarily at presynaptic terminals in the central nervous system. It has been implicated in the pathophysiology of many neurodegenerative disorders, including Parkinson's disease and dementia with Lewy-bodies, collectively referred to as synucleinopathies. As neurodegenerative disorders like Parkinson's disease are charecterized by progressive neuropathological a…

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S Nuber, T Schmidt, H.W Habbes, M Löbbecke-Schumacher, P Teismann, J.B Schulz, B.J Pichler, M Neumann, M Fendt, D Berg, C Holzmann, U Grasshoff, J Boy, I Schmitt, A Bornemann, F Zimmermann, W Kuhn, S Prusiner, E Petrasch-Parwez, O Riess (2005) Conditional control of human wildtype and mutated [A30P] alpha-synuclein in a mouse model of Parkinson's disease. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919318

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