CareLit · DOI-Nachweis · Aktuelle Neurologie
Cell specific promoter mediated transgene expression for gene therapy purposes in the CNS
DOI 10.1055/s-2005-919379
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Nachweis in CareLit
Autor:innenS Schmitz, A Winkeler, A Jacobs
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The aim of this project is specific gene-expression in neurons or glial cells mediated by cell type specific promoters in HSV-1 (Herpes simplex virus type-1) amplicon vectors. Because of the overall goal of gene therapy in the central nervous system, the fusion gene tg17 consisting of the cell culture marker gene gfp and the PET marker gene HSV-1-tk (thymidine kinase) served as reporter. TK can be used for non-invas…
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Zitierempfehlung
S Schmitz, A Winkeler, A Jacobs (2005) Cell specific promoter mediated transgene expression for gene therapy purposes in the CNS. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919379
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