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Limited protection of TAT-Bcl-XL against pneumolysin-induced neuronal cell death

S Ebert, G Dietz, T Mitchell, U Michel, M Bähr, R Nau · Aktuelle Neurologie · Ausgabe 10/2005

DOI 10.1055/s-2005-919421

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Autor:innenS Ebert, G Dietz, T Mitchell, U Michel, M Bähr, R Nau
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Objectives: The severe brain damage that patients with pneumococcal meninigits often suffer is in part caused by the cytosolic pneumococcal protein pneumolysin. The devastating effect of this neurotoxin might be alleviated by interfering with the death pathways that it sets in motion. An important player in these death pathways is Bcl-XL, an antiapoptotic protein of the Bcl-2 family, which is neuroprotective in vari…

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Zitierempfehlung

S Ebert, G Dietz, T Mitchell, U Michel, M Bähr, R Nau (2005) Limited protection of TAT-Bcl-XL against pneumolysin-induced neuronal cell death. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919421

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