CareLit · DOI-Nachweis · Aktuelle Neurologie
Ropinirole: another neuroprotectant blocking the permeability transition pore in the inner mitochondrial membrane
DOI 10.1055/s-2005-919524
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Siemen, S Parvez, K Winkler-Stuck, I Trieu, C Wallesch, P Schönfeld
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
More and more neuroprotectants are found that seem to act by interrupting the signaling chain leading to apoptosis. A central step within this cascade is opening of the permeability transition pore (PTP). In contrast, blockade of the PTP is able to suppress apoptotic cell death as was shown with melatonin (Andrabi et al., 2004, FASEB J, 18:869). After demonstrating such an effect for the dopamine agonist pramipexole…
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Zitierempfehlung
D Siemen, S Parvez, K Winkler-Stuck, I Trieu, C Wallesch, P Schönfeld (2005) Ropinirole: another neuroprotectant blocking the permeability transition pore in the inner mitochondrial membrane. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919524
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