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Pioglitazone reduces the transmigratory capacity of activated T cells in an in-vitro model of the blood-brain-barrier

L Klotz, L Diehl, B Engelhardt, P Knolle, T Klockgether · Aktuelle Neurologie · Ausgabe 10/2005

DOI 10.1055/s-2005-919608

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Autor:innenL Klotz, L Diehl, B Engelhardt, P Knolle, T Klockgether
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The peroxisomal proliferator-activated receptor gamma (PPARg) belongs to a group of ligand-activated transcription factors expressed in lymphocytes, monocytes, dendritic cells and endothelial cells. Several antiinflammatory and antiproliferative effects of PPARg agonists on lymphocytes from multiple sclerosis (MS) patients have already been characterized. Interestingly, oral treatment with PPARg agonists like piogli…

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L Klotz, L Diehl, B Engelhardt, P Knolle, T Klockgether (2005) Pioglitazone reduces the transmigratory capacity of activated T cells in an in-vitro model of the blood-brain-barrier. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919608

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