CareLit · DOI-Nachweis · Aktuelle Neurologie
Novel therapeutic strategies and towards a disease severity marker in a model of Charcot-Marie-Tooth disease 1A (CMT1A)
DOI 10.1055/s-2005-919616
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Nachweis in CareLit
Autor:innenG Meyer zu Hörste, T Prukop, M.W Sereda, K.A Nave
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Charcot-Marie-Tooth disease (CMT) is the most common inherited neuropathy that is associated with a partial duplication of human chromosome 17 (CMT subtype 1A). Previously, we generated a transgenic rat model ('CMT rat') of CMT1A by overexpressing the peripheral myelin protein of 22 KDa (PMP22), the responsible disease gene. We used the CMT rat to explore novel therapeutic options in CMT1A. In a proof-of-principle s…
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Zitierempfehlung
G Meyer zu Hörste, T Prukop, M.W Sereda, K.A Nave (2005) Novel therapeutic strategies and towards a disease severity marker in a model of Charcot-Marie-Tooth disease 1A (CMT1A). Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919616
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