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Biomarkers for axonal damage in amyotrophic lateral sclerosis indicate upper motor neuron involvement and correlate with disease progression

J Brettschneider, A Petzold, S.D Süssmuth, A.C Ludolph, H Tumani · Aktuelle Neurologie · Ausgabe 10/2005

DOI 10.1055/s-2005-919643

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Autor:innenJ Brettschneider, A Petzold, S.D Süssmuth, A.C Ludolph, H Tumani
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Amyotrophic lateral sclerosis is a neurodegenerative disease characterized by the loss of motor neurons located in the spinal cord, brainstem and motor cortex. This study tested whether biomarkers for axonal degeneration correlate with clinical subtypes and are of prognostic value regarding progression of disease. Patients with ALS (N=69) and age-matched controls (N=33) were included into this prospective study. Cer…

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J Brettschneider, A Petzold, S.D Süssmuth, A.C Ludolph, H Tumani (2005) Biomarkers for axonal damage in amyotrophic lateral sclerosis indicate upper motor neuron involvement and correlate with disease progression. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919643

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