CareLit · DOI-Nachweis · Aktuelle Neurologie
Immune escape of malignant gliomas – regulation of NKG2D ligands by TGF-beta and matrix metalloproteinases
DOI 10.1055/s-2005-919651
Bibliografische Angaben
Nachweis in CareLit
Autor:innenG Eisele, J Wischhusen, M Mittelbronn, R Meyermann, A Steinle, M Weller, M.A Friese
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Gliomas are the most frequent primary brain tumors with an incidence of up to 5 per 100.000. For tumorigenesis escape from immunosurveillance is essential. A major mediator of anti-tumor immunity is the lectin-like NKG2D immunoreceptor which is expressed by natural killer (NK) and CD8+ alpha/beta and gamma/delta T cells. NKG2D ligands (NKG2DL) are absent from somatic cells (with the exception of the intestinal epith…
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Zitierempfehlung
G Eisele, J Wischhusen, M Mittelbronn, R Meyermann, A Steinle, M Weller, M.A Friese (2005) Immune escape of malignant gliomas – regulation of NKG2D ligands by TGF-beta and matrix metalloproteinases. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919651
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