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Impaired L-arginine induced vasoreactivity suggests endothelial dysfunction in CADASIL

N Peters, T Freilinger, C Opherk, A Gschwendtner, T Pfefferkorn, M Dichgans · Aktuelle Neurologie · Ausgabe 10/2005

DOI 10.1055/s-2005-919694

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Autor:innenN Peters, T Freilinger, C Opherk, A Gschwendtner, T Pfefferkorn, M Dichgans
ZeitschriftAktuelle Neurologie
Ausgabe10/2005
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Mutations in the Notch3 gene are the cause of CADASIL, a hereditary microangiopathy leading to stroke and vascular dementia. The disease is characterized by ultrastructural granular deposits within small arterial vessels and degeneration of vascular smooth muscle cells. Little is known about endothelial function in CADASIL. Vasoreactivitiy induced by L-Arginine, which is the substrate for endothelial NO…

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N Peters, T Freilinger, C Opherk, A Gschwendtner, T Pfefferkorn, M Dichgans (2005) Impaired L-arginine induced vasoreactivity suggests endothelial dysfunction in CADASIL. Aktuelle Neurologie (10). https://doi.org/10.1055/s-2005-919694

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