CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Malignant transformation of primary human oral squamous epithelial cells using a defined set of genetic alterations
DOI 10.1055/s-2005-919794
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Autor:innenG Goessel, M Quante, A von Werder, S Heeg, M Doebele, M Doebele, C Fulda, H Nakagawa, Y Suliman, AK Rustgi, WC Hahn, HE Blum, O Opitz
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Normal keratinocytes display a restricted replicative life span. Therefore, senescence has been thought to form a barrier against carcinogenesis and the acquisition of cellular immortalization is considered an essential step in the malignant transformation of normal cells. Several groups have demonstrated that the serial introduction of the SV40 early region, H-rasV12 and h-TERT sufficed to transform several types o…
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Zitierempfehlung
G Goessel, M Quante, A von Werder, S Heeg, M Doebele, M Doebele, C Fulda, H Nakagawa, Y Suliman, AK Rustgi, WC Hahn, HE Blum, O Opitz (2006) Malignant transformation of primary human oral squamous epithelial cells using a defined set of genetic alterations. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919794
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