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Mismatch of gastric acid and duodenal bicarbonate secretory capacity in aging telomerase-deficient mice

B Tuo, R Engelhardt, Z Yu, M Djojosubroto, MP Manns, KL Rudolph, U Seidler · Zeitschrift für Gastroenterologie · Ausgabe 04/2006

DOI 10.1055/s-2005-919797

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Autor:innenB Tuo, R Engelhardt, Z Yu, M Djojosubroto, MP Manns, KL Rudolph, U Seidler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: The incidence of non H.p-related duodenal ulcers strongly increases with age and life stress, but the study of its pathophysiology has been hampered by the lack of suitable animal models. Telomere shortening has recently been demonstrated to occur during normal ageing, to be accelerated by high stress levels, and, in telomerase-deficient (TERC -/-) mice, to be associated with increased tissue vulnerabili…

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B Tuo, R Engelhardt, Z Yu, M Djojosubroto, MP Manns, KL Rudolph, U Seidler (2006) Mismatch of gastric acid and duodenal bicarbonate secretory capacity in aging telomerase-deficient mice. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919797

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