CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Tumor derived TGF-beta induces the conversion of tumor infiltrating CD4 T cells into FoxP3+ regulatory T cells
DOI 10.1055/s-2005-919828
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Nachweis in CareLit
Autor:innenC Becker, MC Fantini, C Schramm, PR Galle, MF Neurath
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
CD4+CD25+ regulatory T cells play an important role in the tolerance of the immune system towards tumors. These regulatory T cells specifically express the transcription factor FoxP3 and are believed to be generated in the thymus. However recent data have demonstrated that peripheral T cells can convert into regulatory T cells. Here we demonstrate the TGF-beta dependent induction of FoxP3+ regulatory T cells in the…
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Zitierempfehlung
C Becker, MC Fantini, C Schramm, PR Galle, MF Neurath (2006) Tumor derived TGF-beta induces the conversion of tumor infiltrating CD4 T cells into FoxP3+ regulatory T cells. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919828
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