CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The PDZ-domain binding protein PDZK1/CAP70 is involved in the regulation of murine intestinal NHE3 and CFTR function
DOI 10.1055/s-2005-919844
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Cinar, J Hillesheim, B Tuo, B Riederer, MP Manns, O Kocher, U Seidler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The molecular mechanisms of secretory diarrhea are stimulation of intestinal anion secretion – predominantly via CFTR Cl- channel activation–and an inhibition of salt absorption – predominantly via Na+/H+ exchanger isoform NHE3 inhibition. Recent investigations revealed a regulatory function of each of three PDZ-binding proteins, namely NHERF1, 2 and PDZK1, in transport rate regulation and trafficking of…
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Zitierempfehlung
A Cinar, J Hillesheim, B Tuo, B Riederer, MP Manns, O Kocher, U Seidler (2006) The PDZ-domain binding protein PDZK1/CAP70 is involved in the regulation of murine intestinal NHE3 and CFTR function. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919844
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