CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
cAMP-dependent inhibition of surface cell NHE3 and mucosal PDZ-domain binding protein expression levels are reduced in CFTR deficient murine colon
DOI 10.1055/s-2005-919888
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Autor:innenO Bachmann, B Riederer, G Ziesmann, WH Colledge, MP Manns, U Seidler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
cAMP-dependent inhibition of electroneutral NaCl-absorption in the intestine by Na+/H+ exchange is regulated by a multiprotein complex consisting of transport and adapter proteins, cytoskeletal structures, and protein kinases, and represents a central pathomechanism in secretory diarrhea. This inhibition is lacking in intact sheets of intestinal mucosa from CFTR-deficient mice. Studies in renal and pancreatic cell l…
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Zitierempfehlung
O Bachmann, B Riederer, G Ziesmann, WH Colledge, MP Manns, U Seidler (2006) cAMP-dependent inhibition of surface cell NHE3 and mucosal PDZ-domain binding protein expression levels are reduced in CFTR deficient murine colon. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919888
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