CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The pharmacogenetics of methotrexate in inflammatory bowel disease
DOI 10.1055/s-2005-919908
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Nachweis in CareLit
Autor:innenK Herrlinger, JRF Cummings, MCNM Barnardo, M Schwab, T Ahmad, DP Jewell
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Objectives: Methotrexate (MTX) is an effective second line immunosuppressive treatment in chronic active inflammatory bowel disease (IBD) but its use is limited by unpredictable toxicity and efficacy. MTX metabolism is complex involving a number of enzymes. An individual’s response to MTX may in part be genetically determined by functional genetic variation in genes encoding these enzymes. We report a pharmacogeneti…
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Zitierempfehlung
K Herrlinger, JRF Cummings, MCNM Barnardo, M Schwab, T Ahmad, DP Jewell (2006) The pharmacogenetics of methotrexate in inflammatory bowel disease. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919908
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