CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The Met196Arg Variation of human TNFR2 confers increased apoptotic signaling and impaired TNF-alpha responses: implication for inflammatory bowel disease
DOI 10.1055/s-2005-919936
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Autor:innenPC Rosenstiel, A Till, A Krippner-Heidenreich, H Schäfer, D Seegert, S Schreiber
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background & Aims: Tumor necrosis factor-a (TNF-a)-induced signalling is pivotally involved in the pathogenesis of human chronic inflammatory bowel disease (IBD). Selective upregulation of TNF receptor 2 (TNFR2) in colonic epithelial cells has been described to play an important role in epithelial migration (Corredor et al., 2003) and colonic inflammation-associated alteration in the intestinal epithelium (Mizoguchi…
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Zitierempfehlung
PC Rosenstiel, A Till, A Krippner-Heidenreich, H Schäfer, D Seegert, S Schreiber (2006) The Met196Arg Variation of human TNFR2 confers increased apoptotic signaling and impaired TNF-alpha responses: implication for inflammatory bowel disease. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919936
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