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Questioning Current Concepts in Acute Pancreatitis: Endotoxin Contamination of Porcine Pancreatic Elastase is Responsible for Experimental Pancreatitis-Associated Distant Organ Failure

F Geisler, H Algül, M Riemann, RM Schmid · Zeitschrift für Gastroenterologie · Ausgabe 04/2006

DOI 10.1055/s-2005-919961

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Autor:innenF Geisler, H Algül, M Riemann, RM Schmid
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben

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Aims: The systemic inflammatory response syndrome (SIRS) is responsible for pancreatitis-associated mortality. Recent in vitro and in vivo studies have suggested that pancreatic elastase is one missing link between the localized inflammatory process in the pancreas and distant organ dysfunction and failure. It has been shown that pancreatic elastase activates transcription factors including NF-κB, induces TNF secret…

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F Geisler, H Algül, M Riemann, RM Schmid (2006) Questioning Current Concepts in Acute Pancreatitis: Endotoxin Contamination of Porcine Pancreatic Elastase is Responsible for Experimental Pancreatitis-Associated Distant Organ Failure. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919961

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