CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Lentiviral Gene Transfer is a Novel Strategy in Preventing Liver Fibrosis in LEC Rats Modeling Wilson Disease
DOI 10.1055/s-2005-919984
Bibliografische Angaben
Nachweis in CareLit
Autor:innenU Merle, J Encke, M Volkmann, L Naldini, W Stremmel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: To establish an efficient gene therapy in Wilson disease, the Long-Evans Cinnamon (LEC) rat model was used. We hypothesized that lentiviral gene therapy would improve liver disease and copper excretion in Wilson disease. Cell therapy was compared to systemic gene transfer for their ability to prevent liver cirrhosis. Methods: LEC rats with and without partial hepatectomy were treated either by sys…
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Zitierempfehlung
U Merle, J Encke, M Volkmann, L Naldini, W Stremmel (2006) Lentiviral Gene Transfer is a Novel Strategy in Preventing Liver Fibrosis in LEC Rats Modeling Wilson Disease. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919984
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