CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Combined HCV Cofactor Directed Sirnas Significantly Enhance the Inhibitory Effect of Single Sirnas on Hepatitis C Virus Subgenomic Replication and Translation
DOI 10.1055/s-2005-919985
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Korf, D Jarczak, MP Manns, M Krüger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background/Aims: Persistent infection with hepatitis C virus (HCV) leads to the development of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. SiRNAs are currently being evaluated as promising therapeutic agents for HCV infection. Unfortunately, the antiviral efficacy of HCV directed siRNAs is limited by emergence of escape variants that are resistant to siRNA because of the high mutation rate of HC…
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Zitierempfehlung
M Korf, D Jarczak, MP Manns, M Krüger (2006) Combined HCV Cofactor Directed Sirnas Significantly Enhance the Inhibitory Effect of Single Sirnas on Hepatitis C Virus Subgenomic Replication and Translation. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-919985
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