CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The N-Acetylcysteine sensitive TGF-β receptor endoglin shows a defined expression pattern in liver cells
DOI 10.1055/s-2005-920022
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Autor:innenSK Meurer, AM Gressner, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: TGF-β is the major cytokine regulating hepatic stellate cell (HSC) function in the course of liver fibrogenesis [1]. In a previous study we demonstrated that the reducing substance N-Acetylcysteine (NAC) is able to block TGF-β signaling in HSC by different means than modification of the cellular redox state. As one target we could identify the type III receptor, endoglin, which is expressed in HSC and…
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Zitierempfehlung
SK Meurer, AM Gressner, R Weiskirchen (2006) The N-Acetylcysteine sensitive TGF-β receptor endoglin shows a defined expression pattern in liver cells. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920022
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