CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
A conditional mouse model to study murine hemochromatosis
DOI 10.1055/s-2005-920024
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Autor:innenT Herrmann, M Vujic Spasic, J Kiss, M Hentze, M Muckenthaler, W Stremmel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aims: Hereditary hemochromatosis (HH) is a common iron overload disorder that is most frequently caused by mutations in the HFE gene. Work from our lab and others demonstrates that HFE is required for appropriate hepatic expression of the iron hormone and anti-microbial peptide hepcidin: expression of this negative regulator of duodenal iron absorption is decreased and cannot be adjusted in response to elevated hepa…
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Zitierempfehlung
T Herrmann, M Vujic Spasic, J Kiss, M Hentze, M Muckenthaler, W Stremmel (2006) A conditional mouse model to study murine hemochromatosis. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920024
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