CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Inhibition of Subgenomic HCV Replication Cycle by Sirnas Targeting Highly Conserved HCV Sequence can be Increased by Combination with Hairpin Ribozymes
DOI 10.1055/s-2005-920026
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Autor:innenM Korf, D Jarczak, MP Manns, M Krüger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background/Aims: Hepatitis C Virus (HCV) is an important cause of liver disease. RNA-directed antiviral strategies are suited to inhibit HCV replication cycle since HCV replicates in the cytoplasm of liver cells without integration into the host genome. We previously showed that siRNAs and ribozymes directed against the untranslated HCV 5' and 3'UTR reduced efficiently HCV RNA and Protein levels in HCV replicon cell…
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Zitierempfehlung
M Korf, D Jarczak, MP Manns, M Krüger (2006) Inhibition of Subgenomic HCV Replication Cycle by Sirnas Targeting Highly Conserved HCV Sequence can be Increased by Combination with Hairpin Ribozymes. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920026
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