CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Pleiotrophin/Heparin affin regulatory peptide (HARP) in cultured rat hepatic stellate cells is upregulated under hypoxia and PDGF stimulation: Implication for the early phase of liver fibrogenesis
DOI 10.1055/s-2005-920028
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Nachweis in CareLit
Autor:innenM Antoine, CG Tag, W Wirz, M Mavituna, I Sawitza, AM Gressner, R Müller, P Kiefer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Pleiotrophin (PTN) is a secretory heparin binding protein with various biological activities including mitogenesis, angiogenesis, differentiation, transformation, and cell survival. Employing a rat cell culture model of hepatic stellate cells (HSC) transdifferentiation, we found that PTN transcription is rapidly down-regulated in activated HSCs and in fully transdifferentiated myofibroblasts (MFB). However, release…
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Zitierempfehlung
M Antoine, CG Tag, W Wirz, M Mavituna, I Sawitza, AM Gressner, R Müller, P Kiefer (2006) Pleiotrophin/Heparin affin regulatory peptide (HARP) in cultured rat hepatic stellate cells is upregulated under hypoxia and PDGF stimulation: Implication for the early phase of liver fibrogenesis. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920028
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