CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Glycochenodeoxycholic Acid Induces Transcription of CFOS/JUNB in a Human Hepatoma Cell Line
DOI 10.1055/s-2005-920034
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Autor:innenC Bernt, T Vennegerts, U Beuers, C Rust
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background & Aims: Glycochenodeoxycholic acid (GCDCA) is the major hydrophobic bile acid in human cholestasis and induces apoptosis in hepatocytes at low micromolar concentrations. The transcription factor activator protein 1 (AP–1) is a key regulator of cell cyle and modulates gene transcription associated with apoptosis. The effect of GCDCA on AP–1 expression in hepatocytes is unknown. Thus, the aim of this study…
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Zitierempfehlung
C Bernt, T Vennegerts, U Beuers, C Rust (2006) Glycochenodeoxycholic Acid Induces Transcription of CFOS/JUNB in a Human Hepatoma Cell Line. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920034
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