CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TGF-beta-induced apoptosis can be mediated via TRAIL in hepatoma cells
DOI 10.1055/s-2005-920045
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Autor:innenK Herzer, A Grosse-Wilde, T Ganten, H Schulze-Bergkamen, H Walczak, PH Krammer
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
TGF-beta is a pleiotropic cytokine that is involved in the development of liver cirrhosis and of tumors in different organs. TGF-beta suppresses the immune response and supports immune escape of certain tumors. Moreover, TGF-beta has been shown to induce apoptosis in transformed hepatocytes. However, the mechanism by which apoptosis is induced is largely unknown. We examined whether death receptor-ligand systems pla…
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Zitierempfehlung
K Herzer, A Grosse-Wilde, T Ganten, H Schulze-Bergkamen, H Walczak, PH Krammer (2006) TGF-beta-induced apoptosis can be mediated via TRAIL in hepatoma cells. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920045
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