CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Inhibition of Hepatitis C Virus Subgenomic Replication Cycle by Constitutive Transport Element Linked Ribozymes Targeting Highly Conserved 5' and 3' Untranslated Regions
DOI 10.1055/s-2005-920052
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Nachweis in CareLit
Autor:innenD Jarczak, M Korf, MP Manns, M Krüger
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe04/2006
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background/Aims: The infection with Hepatitis C Virus (HCV) can lead to the development of chronic liver disease with limited therapeutic options in a significant proportion of patients. Hairpin ribozymes (Rz) are small RNA molecules with endonuclease activity that can be engineered to specifically cleave RNA sequences. However, activity depends on Rz expression, target colocalization and cleavage site accessibility…
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Zitierempfehlung
D Jarczak, M Korf, MP Manns, M Krüger (2006) Inhibition of Hepatitis C Virus Subgenomic Replication Cycle by Constitutive Transport Element Linked Ribozymes Targeting Highly Conserved 5' and 3' Untranslated Regions. Zeitschrift für Gastroenterologie (04). https://doi.org/10.1055/s-2005-920052
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